April 25th and 26th 2022
Three invited speakers, 15 oral talks, and one poster session.
NextGenBiocat 2022 Programme
MONDAY APRIL 25TH
| TIME | all times are CET |
| 08:30 | REGISTRATION |
| 09:00 – 09:15 | WELCOME AND OPENING REMARKS |
| SESSION 1 Chair: Caroline E. Paul | |
| 09:15 – 09:50 | INVITED LECTURE – IL1 Marc Garcia-Borràs (University of Girona) Computational Characterization of Enzymatic Reactive Intermediates for the Discovery and Design of New Biocatalytic Activities |
| 09:50 – 10:10 | LECTURE – OP1 H. Adrian Bunzel (University of Bristol) De novo Enzymes by Design and Evolution |
| 10:10 – 10:30 | LECTURE – OP2 Stephan Heijl (Bio-Prodict BV) Protein Engineering with Machine Learning & Bio-Prodict 3DM |
| 10:30 – 11:00 | COFFEE BREAK |
| SESSION 2 Chair: Christoph K. Winkler | |
| 11:00 – 11:20 | LECTURE – OP3 Ben Ashley (University of Edinburgh) Semi-Rational Engineering of a Highly Thermostable Claisen Condensation Biocatalyst Expands Substrate Promiscuity, Improves Activity and Thermostability |
| 11:20 – 11:40 | LECTURE – OP4 Matteo Trande (University of Manchester) Silicatein- α protein as a biocatalyst for organolsiloxanes manipulation, improving ist solubility by protein engineering |
| 11:40 – 12:00 | LECTURE – OP5 Rocío L. Domene (CICbiomaGUNE) Engineered metalloproteins as artificial biocatalysts |
| 12:00 – 13:00 | LUNCH @ Café X |
| SESSION 3 Chair: Sandy Schmidt | |
| 13:00 – 13:35 | INVITED LECTURE – IL2 Kristina Haslinger (University of Groningen) Natural product tailoring through enzymatic methylation in E. coli cell factories |
| 13:35 – 13:55 | LECTURE – OP6 Benoît Desguin (UCLouvain) Biosynthesis and Function of The Nickel-Pincer Cofactor |
| 13:55 – 14:15 | LECTURE – OP7 Ines B. Folger (ETH Zurich) High-Throughput Reprogramming of NRPS Condensation Domains |
| 14:15 – 14:40 | COFFEE BREAK |
| SESSION 4 Chair: Sarah Bierbaumer and Pablo Díaz-Kruik | |
| 14:40 – 15:00 | LECTURE – OP8 Max Lubberink (University of Manchester) Re-tasking of Carboxylic Acid Reductase for Amide Bond formation |
| 15:00 – 15:20 | LECTURE – OP9 Martin Toul (Masaryk University) Global Kinetic Analysis to Reveal an Extended Biocatalytic Mechanism and a True Limitation: Staphylokinase Case |
| 15:20 – 15:40 | LECTURE – OP10 Jiaming Peng (University of Basel) Fluorinated S-Adenosylmethionine as a Reagent for Enzyme-Catalyzed Fluoromethylation |
| 15:40 – 16:00 | TRANSITION TO POSTER VENUE (TU Delft Aula) |
| 16:00 – 17:30 | POSTER SESSION Aula |
| 17:30 – 19:00 | BORREL (Dutch aperitif) transition to the Botanical garden |
| 19:00 | CONFERENCE DINNER Botanical Garden |
TUESDAY APRIL 26TH
| TIME | all times are CET |
| 08:30 – 08:45 | WELCOME |
| SESSION 5 Chair: Ana I. Benítez-Mateos | |
| 08:45 – 09:20 | INVITED LECTURE – IL3 Juan M. Bolivar (Complutense University of Madrid) Engineering of immobilized enzyme biocatalysts for reaction intensification |
| 09:20 – 09:40 | LECTURE – OP11 Katharina Ebner (Bisy) From database search to enzyme kit – Challenges and achievements leading to the development of a new UPO enzyme panel |
| 09:40 – 10:00 | LECTURE – OP12 Laura Rotilio (University of Pavia) Structural and biochemical studies enlighten the unspecific peroxygenase from Hypoxylon sp. EC38 as an efficient oxidative biocatalyst |
| 10:00 – 10:30 | COFFEE BREAK |
| SESSION 6 Chair: Christian M. Heckmann | |
| 10:30 – 10:50 | LECTURE – OP13 Ewald P.J. Jongkind (Delft University of Technology) Synthesis of Chiral Amines via a Bi-Enzymatic Cascade Using an Ene-Reductase and Amine Dehydrogenase |
| 10:50 – 11:10 | LECTURE – OP14 Jack S. Rowbotham (University of Manchester) Bio- and ChemoBio-hybrid catalysis for atom-efficient synthesis of complex isotopically labelled molecules |
| 11:40 – 12:00 | LECTURE – OP15 Morten van Schie (Centrient Pharmaceuticals) How to Build a Biocatalysis Laboratory from Scratch |
| 12:00 – 12:30 | CLOSING Caroline E. Paul, Ana I. Benítez-Mateos |
| 12:30 | LUNCH @ Café X |
NextGenBiocat 